Jianming Xu Selected Research

Steroid Receptors (Steroid Receptor)

6/2021	Steroid Receptor Coactivator-3 Is Required for Inhibition of the Intestinal Muscularis Inflammatory Response of Postoperative Ileus in Mice.
1/2021	Development of improved SRC-3 inhibitors as breast cancer therapeutic agents.
1/2016	SRC-1 Regulates Blood Pressure and Aortic Stiffness in Female Mice.
8/2015	Characterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death.
1/2015	Steroid Receptor Coactivator-3 (SRC-3/AIB1) as a Novel Therapeutic Target in Triple Negative Breast Cancer and Its Inhibition with a Phospho-Bufalin Prodrug.
5/2014	Global gene repression by the steroid receptor coactivator SRC-1 promotes oncogenesis.
3/2014	Bufalin is a potent small-molecule inhibitor of the steroid receptor coactivators SRC-3 and SRC-1.
1/2014	The steroid receptor coactivator-3 is required for developing neuroendocrine tumor in the mouse prostate.
7/2013	The steroid receptor coactivator-3 is required for the development of castration-resistant prostate cancer.
1/2013	Steroid receptor coactivator-1 mediates estrogenic actions to prevent body weight gain in female mice.

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Jianming Xu Research Topics

Disease

98	Neoplasms (Cancer) 09/2022 - 11/2002
31	Breast Neoplasms (Breast Cancer) 01/2022 - 03/2004
30	Neoplasm Metastasis (Metastasis) 10/2021 - 03/2004
22	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 06/2014
15	Stomach Neoplasms (Stomach Cancer) 04/2022 - 09/2013
15	Hypertension (High Blood Pressure) 11/2021 - 01/2013
14	Carcinogenesis 01/2022 - 03/2004
11	Disease Progression 01/2022 - 01/2013
10	Hepatocellular Carcinoma (Hepatoma) 01/2021 - 01/2009
9	Adenocarcinoma 01/2020 - 10/2014
7	Esophageal Squamous Cell Carcinoma 01/2022 - 08/2016
7	Proteinuria 11/2021 - 01/2017
6	Neuroendocrine Tumors (Neuroendocrine Tumor) 01/2022 - 01/2014
6	Body Weight (Weight, Body) 07/2021 - 08/2006
6	Inflammation (Inflammations) 06/2021 - 06/2010
6	Prostatic Neoplasms (Prostate Cancer) 01/2019 - 06/2007
5	Fibrosis (Cirrhosis) 02/2021 - 08/2009
4	Infections 06/2022 - 08/2017
4	Colitis 01/2022 - 01/2013
4	Diarrhea 01/2022 - 12/2014
4	Ulcerative Colitis 01/2019 - 01/2012
3	Carcinoma (Carcinomatosis) 05/2021 - 04/2011
3	Asthma (Bronchial Asthma) 02/2021 - 01/2012
3	Hepatitis B 01/2021 - 11/2013
3	Exanthema (Rash) 01/2019 - 10/2014
3	Pancreatic Neoplasms (Pancreatic Cancer) 12/2017 - 11/2014
3	Hyperplasia 01/2014 - 09/2003
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 04/2022 - 06/2012
2	Weight Gain 12/2021 - 03/2005
2	Circulating Neoplastic Cells 12/2021 - 01/2018

Drug/Important Bio-Agent (IBA)

26	Steroid Receptors (Steroid Receptor)IBA 06/2021 - 06/2002
21	Proteins (Proteins, Gene)FDA Link 05/2021 - 04/2003
15	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 01/2022 - 11/2002
14	Biomarkers (Surrogate Marker)IBA 04/2022 - 10/2014
13	Transcription Factors (Transcription Factor)IBA 05/2021 - 02/2004
9	Leucovorin (Folinic Acid)FDA Link 05/2019 - 06/2014
9	Estrogen ReceptorsIBA 01/2015 - 10/2004
8	CytokinesIBA 09/2021 - 12/2002
8	Oxaliplatin (Eloxatin)FDA LinkGeneric 12/2020 - 06/2014
8	Fluorouracil (Carac)FDA LinkGeneric 01/2020 - 04/2011
8	Nuclear Receptor Coactivator 3IBA 01/2017 - 09/2005
7	Immune Checkpoint InhibitorsIBA 01/2022 - 05/2017
7	apatinibIBA 01/2021 - 09/2013
7	Cisplatin (Platino)FDA LinkGeneric 01/2020 - 04/2011
7	Estrogens (Estrogen)FDA Link 12/2019 - 06/2002
7	Messenger RNA (mRNA)IBA 01/2019 - 04/2002
6	surufatinibIBA 01/2022 - 01/2019
6	Monoclonal AntibodiesIBA 01/2022 - 01/2017
6	Sorafenib (BAY 43-9006)FDA Link 01/2021 - 01/2009
6	Capecitabine (Xeloda)FDA Link 12/2020 - 10/2014
6	Pharmaceutical PreparationsIBA 08/2020 - 01/2009
6	Hormones (Hormone)IBA 08/2017 - 03/2004
5	Aspartate Aminotransferases (Aspartate Transaminase)IBA 11/2021 - 07/2012
5	HMPL-013IBA 05/2021 - 01/2017
5	Irinotecan (Camptosar)FDA LinkGeneric 01/2019 - 11/2014
5	Androgen Receptors (Androgen Receptor)IBA 01/2019 - 02/2004
4	human ERBB2 proteinIBA 11/2021 - 01/2013
4	Alanine Transaminase (SGPT)IBA 08/2020 - 07/2012
4	Cetuximab (Erbitux)FDA Link 01/2020 - 10/2014
4	Histones (Histone)IBA 11/2019 - 01/2012
4	Trastuzumab (Herceptin)FDA Link 05/2019 - 08/2011
4	AndrogensIBA 01/2019 - 01/2009
4	Insulin-Like Growth Factor I (IGF-1)IBA 08/2011 - 03/2004
3	B7-H1 AntigenIBA 01/2022 - 12/2021
3	Paclitaxel (Taxol)FDA LinkGeneric 01/2022 - 01/2015
3	Nuclear Receptor Coactivator 1IBA 01/2022 - 07/2015
3	AcidsIBA 01/2022 - 11/2016
3	sintilimabIBA 01/2022 - 01/2018
3	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 11/2021 - 01/2017
3	BilirubinIBA 11/2021 - 07/2012
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2021 - 10/2013
3	LigandsIBA 09/2021 - 05/2017
3	Biological ProductsIBA 09/2021 - 12/2002
3	camrelizumabIBA 01/2021 - 01/2019
3	Tyrosine Kinase InhibitorsIBA 01/2021 - 05/2016
3	regorafenibIBA 08/2020 - 01/2013
3	CateninsIBA 01/2019 - 07/2015
3	Phenobarbital (Luminal)FDA Link 01/2019 - 01/2014
3	Histone DemethylasesIBA 12/2018 - 10/2017
3	LipidsIBA 12/2018 - 06/2010
3	Proliferating Cell Nuclear Antigen (PCNA)IBA 01/2018 - 05/2008
3	Cyclin D1IBA 01/2018 - 05/2008
3	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 09/2015 - 03/2011
3	Tamoxifen FDA LinkGeneric 01/2015 - 09/2007
3	SteroidsIBA 04/2012 - 11/2008
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 04/2012 - 12/2002
3	Estrogen Receptor alphaIBA 01/2012 - 10/2004
3	Phosphotransferases (Kinase)IBA 06/2011 - 05/2008
3	Tumor Viral Antigens (Large T Antigen)IBA 01/2009 - 10/2004
2	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2022 - 07/2015
2	gallium Ga 68 dotatateIBA 01/2022 - 01/2020
2	Dextrans (Dextran)FDA Link 01/2022 - 07/2015
2	AzoxymethaneIBA 01/2022 - 07/2015
2	Pro-Opiomelanocortin (Proopiomelanocortin)IBA 12/2021 - 12/2019
2	Nuclear Receptor Coactivator 2IBA 12/2021 - 01/2012

Therapy/Procedure

48	Therapeutics 01/2022 - 09/2007
26	Drug Therapy (Chemotherapy) 01/2022 - 04/2011
3	Castration 01/2019 - 07/2013
2	Aftercare (After-Treatment) 06/2022 - 05/2017
2	Immunotherapy 12/2021 - 09/2020